Betadex Sulfobutyl Ether Sodium: Unlocking Unmatched Solubility in Remdesivir and Voriconazole Injection. USP 43-NF 38* Compliance Guaranteed with OHpak SB-803 HQ Column

Betadex sulfobutyl ether sodium plays a crucial role as a solubilizer in the formulation of remdesivir and voriconazole for injection. To ensure compliance with USP 43-NF 38*, betadex sulfobutyl ether sodium assay must be carried out using the L37 packing material. The OHpak SB-803 HQ, a polymer-based aqueous SEC (GFC) column, was used to confirm these requirements and deliver accurate results.

System suitability requirements:
Relative standard deviation (RSD) of the peak area: ≤ 2.0%

*The version at the time of the application acquisition.

Column       : Shodex OHpak SB-803 HQ (8.0 mm I.D. x 300 mm)
Eluent       : 0.1 M potassium nitrate in a mixture of acetonitrile and water (1:4)
Flow rate    : 1.0 mL/min
Detector     : Shodex RI
Column temp. : 35 ℃