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Shodex Replacement for TSK G2000SWXL (Small MW Proteins)

Record: 803

Category: Column Selection
Product: KW-802.5
Sample: Proteins

Question
A customer has been using a 10+ year old TSK G2000SWXL silica SEC column for small proteins. They want a Shodex exclusion column recommendation. In Europe, they also used Sephadex G-75 with good resolution.

Answer
The closest Shodex equivalent to TSK G2000SWXL is the PROTEIN KW-802.5.

  • MW range: ~5,000–100,000 Da (proteins)
  • Exclusion limit: ~1.5 × 10⁵ Da

For slightly larger proteins, the KW-803 may also be considered.

Additional Comments

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