What is the difference between the SB series and LB series SEC columns?

Record: 923

Category: Column Selection
Product: SB-807
Sample: N/A

Question
What is the difference between the SB series and LB series SEC columns?

Answer

Both the SB-800 HQ series and LB-800 series are polymer-based aqueous SEC (GFC) columns, but they are optimized for slightly different purposes:

SB-800 HQ series
- Designed for general aqueous SEC of water-soluble polymers.
- Wide molecular weight coverage (up to ~5×10⁸ Da with SB-807 HQ).
- Suitable for routine applications where broad distribution or very high MW polymers need to be analyzed.
- Example: SB-807 HQ is specifically intended for ultra-high MW polymers, with large gel particles to prevent shear degradation.
LB-800 series
- Also designed for aqueous SEC, but with very low column bleeding, making it ideal for light scattering detection (MALS, DLS).
- Offers cleaner baselines, especially important when detecting low-MW components.
- Same pore size lineup as SB-802.5 through LB-806M, but no LB-807 equivalent.

Additional Comments

Choose SB-series for general aqueous SEC, calibration work, and ultra-high MW polymers (including SB-807 HQ).
Choose LB-series when using light scattering detectors or when minimizing baseline noise is critical.

Applications