Featured columns include our HILIC, Ion Chromatography and polymer reversed phase columns. Please browse through our VN series HILIC columns especially designed for oligo-DNA and oligo-RNA. Moreover, we have a new line of polymer LB series columns for oligosaccharide separation. The LB series is highly uniform for higher plate count and best in class peak resolution.

Click on the L# on the left to view and compare the columns in that category.

No.	Packing material	Recommended column
L1	Octadecyl silane chemically bonded to porous or nonporous silica or ceramic microparticles, 1.5 to 10 μm in diameter, or a monolithic rod.	C18 Silica C18M C18U
L17	Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 6 to 12 μm in diameter.	SUGAR SH1011 SUGAR SH1821 RSpak KC-811
L19	Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 5-15 μm in diameter.	SUGAR SC1011 SUGAR SC1211 EP SC1011-7F USPpak MN-431
L20	Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5-10 μm in diameter, or a monolithic silica rod.	PROTEIN KW-800 series KW400 series PROTEIN LW-803 PROTEIN LW-403 4D
L21	A rigid, spherical styrenedivinylbenzene copolymer, 3 to 30 μm in diameter.	GPC KF-800, KD-800, KF-400HQ, HK-400, LF, RSpak DS-613 RSpak DS-413
L22	A cation-exchange resin made of porous polystyrene gel with sulfonic acid groups, 5-15 μm in diameter.	CXpak P-421S SUGAR SP0810 SUGAR SC1011 SUGAR KS-800 series SUGAR SC1211 SUGAR SZ5532 EP SC1011-7F USPpak MN-431 RSpak DC-613 SUGAR SH1011 SUGAR SH1821 RSpak KC-811
L23	An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quartenary ammonium groups, 7-12 μm in size.	IEC QA-825 IC I-524A
L25	Packing having the capacity to separate compounds with a molecular weight range from 100-5000 (as determined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups) was found suitable.	OHpak SB-802 HQ OHpak SB-802.5 HQ OHpak LB-802.5
L33	Packing having the capacity to separate dextrans by molecular size over a range of 4,000 to 500,000 Da. It is spherical, silica-based, and processed to provide pH stability.	PROTEIN KW-800 series KW400 series PROTEIN LW-803 PROTEIN LW-403 4D
L34	Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form, 7 to 9 μm in diameter.	SUGAR SP0810
L37	Packing having the capacity to separate proteins by molecular size over a range of 2,000 to 40,000 Da. It is a polymethacrylate gel.	OHpak SB-803 HQ OHpak LB-803
L38	A methacrylate-based size-exclusion packing for water-soluble samples.	OHpak SB-800 HQ series OHpak LB-800 series
L39	A hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.	ODP2 HP RSpak DM-614 OHpak SB-800 HQ series OHpak LB-800 series
L45	Beta cyclodextrin, R,S-hydroxypropyl ether derivative, bonded to porous silica particles, 3-10 μm in diameter.	ORpak CDBS-453
L58	Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 6 to 30 μm in diameter.	CXpak P-421S SUGAR KS-800 series RSpak DC-613
L59	Packing for the size-exclusion separations of proteins (separation by molecular weight) over the range of 5 to 7000 kDa. The packing is a spherical 1.5- to 10-μm, silica or hybrid packing with a hydrophilic coating.	PROTEIN KW-800 series KW400 series PROTEIN LW-803 PROTEIN LW-403 4D
L67	Porous vinyl alcohol copolymer with a C18 alkyl group attached to the hydroxyl group of the polymer, 2 to 10 μm in diameter.	Asahipak ODP-50
L71	A rigid, spherical polymetacrylate, 4 to 6 μm in diameter.	RSpak DE-613 RSpak DE-413 RSpak DE-213
L76	Silica based, weak cation-exchange material, 5 μm in diameter. Substrate is surface polymerized polybutadiene-maleic acid to provide carboxylic acid functionalities. Capacity not less than 29 μEq/column.	IC YK-421
L82	Polyamine chemically bonded to cross-linked polyvinyl alcohol polymer, 5 μm in diameter.	Asahipak NH2P-50
L89	Packing having the capacity to separate compounds with a molecular weight range from 100 to 3000 (as determined by polyethylene oxide), applied to neutral and anionic water-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylate ether (surface contains some residual cationic functional groups).	OHpak SB-802.5 HQ OHpak LB-802.5

Characteristics of   Size Exclusion Chromatography
Network or pores on the surface of the   packing material works as molecular sieve to separate molecules based on   their sizes.
To separate molecules solely based on   their sizes, it requires an analytical condition without any compounds and   packing gel interaction.
The bigger the molecule size, the faster   the elution sequence.
Used for molecular weight or molecular   distribution determination of macromolecules and qualification of oligomers.

Shodex™ ligand exchange, ion exclusion and specialized GFC columns can separate sugars from monosaccharides and disaccharides to oligosaccharides and even polysaccharides. Moreover, we offer columns that can separate both organic acids and saccharides simultaneously. Our columns operate in full ligand exchange or ion exclusion mode. Depending on eluent selection some of our column can operate in mixed mode. For example, our KS series that operate in mixed mode ligand exchange and size exclusion. Read more about the features below as well as our column selection guide. Choose the perfect column or columns for your application. Please refer to our HILIC and Gel Filtration product guides for more information about saccharides and organic separations in other modes.

SC1011	Separates saccharides by combination of ligand exchange and size exclusion modes
SP0810	Three types of counter ions are available: Ca2+, Pb2+ and Na+
KS-801	Only water is required for the analysis of neutral sugars
KS-802	SC1011 fulfills USP-NF L19 and L22 requirements
	SP0810 fulfills USP-NF L22 and L34 requirements
	KS-801 and KS-802 fulfill USP-NF L22 and L58 requirements
KS-803	Suitable for separation of polysaccharides by size exclusion mode
KS-804	Can be used in combination with other columns e.g., KS-801 and/or KS-802
	Only water is required for the analysis of neutral sugars
	Fulfill USP-NF L22 and L58 requirements
DC-613	Separates elements by combination of ligand exchange and HILIC modes
	DC-613 can analyze sugars without removing sodium salts in the sample
	SZ5532 is recommended for the separation of disaccharides or trisaccharides
SZ5532	SC1211 is suitable for separating sugar alcohols
	DC-613 fulfills USP-NF L22 and L58 requirements
SC1211	SZ5532 fulfills USP-NF L22 requirements
	SC1211 fulfills USP-NF L19 and L22 requirements
SC1011-7F	Pharmacopoeia method relevant columns
	Ca2+ modified ligand exchange chromatography column
MN-431	Only water is required for the analysis of neutral sugars
	Fulfill USP-NF L19 and L22 requirements

 

Column Selection: by Combination of Saccharides

Saccharides to be separated	Columns to be selected
Monosaccharides
Glu,Fru	SP0810,SC1011,SC1211,KS-801
Glc,Gal,Fru	SP0810,SC1011,SC1211
Glc,Gal,Man	SP0810
Glc,Gal,Ara	SP0810,SC1011,SZ5532
Glc,Xyl,Ara	SP0810,SC1011,SZ5532
Glc,Fru,Sorbitol	SC1011,SC1211,SC1821 (discontinued),SZ5532
Glc,Gal,Sorbitol,Ducitol	SP0810,SC1011
Glc,Gal,Man,Sorbitol,Ducitol,Mannitol	SP0810
Glc,Fru,Gly,EtOH	SC1011,SC1211,KS-801
Glc,Fru+alcohols	SC1011,SH1011,SC1211
Glc,Fru+organic acids	SH1011,SH1821
Disaccharides
Suc,Lac	SZ5532
Suc,Mal	SZ5532
Suc,Mal,Lac	SZ5532
Mal,Isomaltose	SZ5532
Lac,Lactulose	SP0810,SC1011
Suc,Glc,Fru	SC1011,SC1211,KS-801,SZ5532
Suc,Lac,Glc,Gal,Fru	SZ5532
Mal,Glc,Fru,Gly,EtOH	SC1011,SC1211,KS-801
Cel,Glc,Gal,Man,Xyl,Ara	SP0810
Mal,Glc,Fru,Sorbitol	SP0810,SC1011,SC1211,SZ5532
Mal,Glc,Fru+alcohols	SC1011,SC1211,SH1011
Mal,Glc,Fru+organic acids	SH1011,SH1821
Suc,Glc,Fru,Sorbitol	SP0810,SC1011,SC1211,SC1821
Mal,Maltitol	SP0810,SC1011,SC1211,SZ5532
Suc,Lac,Mal,Maltitol	SZ5532
Glc,Suc,Erythrytol	SP0810,SC1011,KS-801
Mal,Glc,Fru,Erythrytol	SP0810,SC1011
Sta,Raf,Mal,Glc,Gal,Ara	SC1011,KS-801,SZ5532
G4,G3,Mal,Glc	SC1011,KS-801,KS-802
Sta,Raf,Suc,Glc	SC1011,KS-801,SZ5532
Raf,Suc,Glc,Fru,Ara	KS-801
Maltooligosaccharide	SC1821 (discontinued),KS-802,SZ5532
Maltooligosaccharide+alcohols	SC1821 (discontinued),KS-802,SH1821
Maltooligosaccharide+organic acids	SH1821
Maltooligosaccharide+sugar alcohols	SC1821 (discontinued),SC1011+KS-802
Xylitol,Sorbitol	SC1011,SC1211,SZ5532
Sobitol,Mannitol,Xylitol	SP0810,SC1211,SZ5532
Sobitol,Dulcitol,Xylitol	SP0810,SC1011,SZ5532
Maltitol,Sorbitol	SC1011,SC1211,SZ5532
Maltitol,Dulcitol,Arabitol,Xylitol,Mannitol,Sorbitol	SC1211

Shodex™ ion chromatography columns are among the best in the industry. We offer both suppressed columns for sensitive anion separations required for water analyses and non-suppressed columns that can be run on traditional HPLC systems equipped with a conductivity detector. Refer to the features for each column and the column selection guide below.  

Column	Feature/Description
NI-424	Ideal for anion non-suppressor methods
I-524A	NI-424 provides simultaneous analysis of fluoride and phosphate ions
	I-524A fulfills USP-NF L23 requirements
SI-90 4E	Suitable for anion suppressor methods with sodium carbonate eluent
SI-50 4E	Suitable for the quantitative analysis of fluoride ion
SI-52 4E	SI-50 4E separates target inorganic anions from organic acids
	SI-52 4E provides simultaneous analysis of oxyhalides and general inorganic ions
SI-35	Rapid-analysis type columns used with suppressor and sodium carbonate eluent
	SI-35 4D provides rapid analysis of oxyhalides and general inorganic ions
	SI-35 2B provides rapid analysis of general inorganic ions
SI-36 4D	Suitable for anion suppressor methods with potassium hydroxide
	Good separation of sulfite and sulfate ions
	Analysis of seven general inorganic anions within 30 minutes under isocratic conditions